The Healthcare Technology Report is pleased to announce The Top 100 Healthcare Technology Companies of 2023. In recent decades, the realm of healthcare technology has undergone remarkable advancements. The convergence of cutting-edge technologies with healthcare has opened up a vast array of possibilities, ranging from real-time monitoring of vital signs through wearable devices to the anticipation of disease outbreaks using AI systems. Looking ahead, it appears that the potential for innovation in healthcare technology knows no bounds. According to latest data, the global healthcare technology market is projected to experience substantial growth, expanding from $371 billion in 2022 to $852 billion in 2027.
Leading the charge in this thriving sector are the recipients of this year's awards. These companies represent a diverse spectrum of entities, including well-established, widely recognized corporations and emerging, yet rapidly expanding enterprises. Nonetheless, what unites these trailblazing companies chosen for this year's roster is their shared commitment to transforming our daily lives and reshaping our approach to a fundamental aspect that affects us all profoundly: our health.
Among this year's recipients of awards, we have RXNT, a true trailblazer in the ambulatory healthcare technology arena. RXNT's platform has facilitated the transmission of over 100 million prescriptions, facilitated over 10 million signed encounters, and consistently processed an average of $300 million in claims each year.
Furthermore, this year we are extending our recognition to Moderna, a rapidly expanding company that has consistently secured its status as a leading biopharmaceutical employer, a feat acknowledged by Science Magazine for eight consecutive years. Although many may be more familiar with Moderna for its mRNA technology, which led to the development and authorization of one of the earliest COVID-19 vaccines during the global pandemic. Lastly, we have Bio-Rad Laboratories, a company whose position as a prominent player in the life science research and clinical diagnostics markets earned it $2.8 billion in revenues for 2022.
Please join us in recognizing The Top 100 Healthcare Technology Companies of 2023.
1. Medtronic
Category: Medical Devices
Headquartered in Minneapolis, Minnesota, Medtronic leads the global healthcare technology industry and fearlessly confronts the most formidable health challenges confronting humanity. Their mission, centered on alleviating pain, restoring health, and extending life, serves as a unifying force for a global workforce comprising over 90,000 dedicated individuals. In all their pursuits, Medtronic remains unwaveringly devoted to engineering the extraordinary.
Medtronic’s global presence enables them to help more people in more places. Organized in four regions, operating in over 150 countries all over the world, with 19 distribution sites and 74 manufacturing sites, they bring innovative and breakthrough technologies and therapies that alleviate pain, restore health, and extend lives.
2. Bristol Myers Squibb
Category: Biotech
Bristol Myers Squibb, a leading pharmaceutical company, is dedicated to transforming the lives of patients through groundbreaking science. With a commitment to innovation, they foster extraordinary careers, offering opportunities that span scientific, business, and support roles. Their diverse team collaborates on a sustainable pipeline of potential therapies, harnessing translational medicine and data analytics to ensure the right treatment reaches the right patient at the right time. BMS operates at the forefront of innovation in oncology, hematology, immunology, cardiovascular disease, and fibrosis.
In recent milestones, the company celebrated a decade of its Coast 2 Coast 4 Cancer Cross-Country Bike Ride, supporting the V Foundation for Cancer Research. Additionally, the U.S. FDA approved Reblozyl® as a first-line treatment for anemia in adults with lower-risk Myelodysplastic Syndromes, and the European Commission granted approval for Opdivo as an adjuvant treatment for completely resected Stage IIB or IIC Melanoma. Bristol Myers Squibb remains dedicated to driving innovation and improving patient lives, embodying its mission at every turn.
3. Access Healthcare
Category: Consumer HealthTech
Access Healthcare provides business process outsourcing, applications services, and robotic process automation tools to hospitals, health systems, providers, payers, and related service providers. The company operates from 19 global delivery centers in the U.S., India, and the Philippines. Their over 25,000 staff members are committed to bringing revenue cycle excellence to clients by leveraging technology, emerging best practices, and global delivery.
Based in Dallas, Texas, the company supports more than 400,000 healthcare providers through 85+ clients, serving 80+ specialties, processing more than $70 billion in accounts receivable annually – and ascribing medical codes to more than 30 million charts annually. With more than 3,500 virtual bots in operation, Access Healthcare's proprietary robotic process automation platform helps its clients improve efficiency. Access Healthcare is HITRUST, PCI DSS, SOC, ISO 27001, and ISO 9001 certified, providing security, availability, and confidentiality of sensitive health information.
4. Bio-Rad Laboratories
Category: Biotech
Bio-Rad Laboratories, based in Hercules, California, is a prominent player in the life science research and clinical diagnostics markets. With a global reach, the company operates in research, development, manufacturing, and sales, supported by a team of over 8,200 employees. In 2022, Bio-Rad generated revenues of $2.8 billion. Their clientele includes universities, research institutions, hospitals, food safety and environmental quality labs, and biopharmaceutical firms. Together, they collaborate on creating high-quality products that advance science and improve lives.
Recent developments for the company include the introduction of StarBright™ Red Dye and an expanded range of antibody markers conjugated to StarBright Dyes, enhancing multiplex flow cytometry and research capabilities. Bio-Rad also launched the IH-500 NEXT Fully Automated System for ID-Cards, strengthening immunohematology laboratory capabilities. The company continues to drive scientific progress and laboratory automation, embodying its mission to empower global research and diagnostics.
5. Teva Pharmaceuticals
Category: Biotech
Teva Pharmaceuticals, a pharmaceutical industry mainstay for over a century, is dedicated to improving global healthcare through medicine development and production. It leads in both generic and specialty medicines, with a portfolio of 3,500 products spanning various therapeutic areas. These medicines benefit roughly 200 million people worldwide daily, managed by one of the industry's most expansive supply chains. In addition to generics, Teva heavily invests in research and operations to bolster its specialty and biopharmaceutical product range.
The core mission is clear: to enhance global patient lives by ensuring access to quality medicines for disease management, infection control, and overall health improvement. Since its founding in 1901, Teva has been proud to serve healthcare providers, patients, and caregivers with accessible generic and innovative products. Their portfolio, around 3,600 products strong, ranks among the world's largest. Nearly 200 million individuals in 60 countries benefit from Teva's high-quality medicines daily, carrying on a century-long legacy of innovation in generic and biopharmaceutical research and development.
6. PCI Pharma Services
Category: Biotech
PCI Pharma Services is a global CDMO that specializes in drug development, manufacturing, and packaging solutions, facilitating product speed to market and commercial success for clients. Headquartered in Philadelphia, PCI employs leading technology to address drug development needs throughout the product life cycle, from manufacturing to clinical trial supply chains and commercialization.
As part of their digital transformation strategy, PCI developed and launched pci | bridgeTM, an innovative digital platform providing customers immediate visibility into their clinical and commercial supply chain. Since then, the platform has evolved tremendously, integrating new digital technologies and enhancing the user experience for their customers.
With over five decades in the healthcare services sector, PCI has a track record of more than 90 successful product launches each year. They operate across 30 sites in seven countries, employing over 5,200 individuals.
Recent developments include the establishment of a new Center of Excellence Facility in the Midwest, expansion of sterile fill-finish capabilities in Melbourne and San Diego, and plans for a new $50 million facility in Rockford, which will create 250 jobs and strengthen PCI's pharmaceutical solutions.
7. BioNTech
Category: Biotech
BioNTech, a German biopharmaceutical company established in 2008, is a leader in next-generation immunotherapy for cancer and other severe illnesses. The company employs cutting-edge computational discovery and therapeutic drug platforms to swiftly create innovative biopharmaceuticals. Their extensive oncology portfolio encompasses mRNA-based therapies, CAR-T cell therapies, immune checkpoint modulators, cancer antibodies, and small molecules. BioNTech collaborates with global pharmaceutical partners like Pfizer, Genentech, and Sanofi to develop mRNA vaccines for infectious diseases.
BioNTech has over 20 product candidates in development, with 8 currently undergoing clinical trials across 17 tumor types, impacting over 250 patients, and supported by a team of over 1100 employees. BioNTech recently gained U.S. FDA approval for the 2023-2024 COVID-19 vaccine in collaboration with Pfizer. Additionally, their acquisition of InstaDeep enhances their AI-powered drug discovery capabilities, reinforcing their status as pioneers in biopharmaceutical innovation. BioNTech continues to advance patient-specific immunotherapies, aiming to revolutionize global healthcare.
8. Boston Scientific
Category: Medical Devices
Boston Scientific, a global medical technology leader with over four decades of experience, is dedicated to transforming lives through innovative medical solutions worldwide. They relentlessly pursue advancements in medical science, offering a wide range of high-performance solutions to meet unmet patient needs and reduce healthcare costs. Notably, collaboration is at the core of Boston Scientific's mission. They work collectively to address the most challenging healthcare issues, providing relief to those with life-threatening conditions and the healthcare professionals who care for them.
Operating in over 100 countries, Boston Scientific empowers healthcare providers to deliver more cost-effective, efficient care, extending access to health services and enhancing the well-being of countless individuals. They also prioritize diversity and inclusivity in their workforce of 38,000+ employees worldwide, while actively encouraging community service. Recent achievements, such as FDA approval for the latest-generation WATCHMAN FLX™ Pro Left Atrial Appendage Closure Device and innovative Image Guided Programming Software for Deep Brain Stimulation, highlight Boston Scientific's unwavering commitment to advancing medical technology for the betterment of humanity.
9. Tebra
Category: Software & Data
In 2021, with a combined mission to unlock better healthcare, Kareo and PatientPop joined forces to form Tebra — a complete practice automation solution for independent healthcare practices and billing companies. Today, Tebra provides the digital tools and support built to help independent practices attract new patients, deliver modern care, get paid quickly, and operate efficiently. From a powerful EHR to cutting-edge automation tools, Tebra’s products come together to form the complete operating system for practice success.
The name Tebra is derived from the word “vertebrae” and symbolizes the role the company serves as the backbone of practice success, delivering digital technology to connect providers and their patients. Headquartered in Southern California, Tebra currently has approximately 1,000 employees supporting close to 150,000 healthcare providers who are delivering care to more than 123 million patients in the U.S.
10. Relias
Category: Software & Data
Relias provides lifelong workforce enablement solutions for more than 11,000 healthcare and human services organizations and 4.5 million caregivers to drive measurable outcomes. Customers use Relias solutions to attract and retain talent, elevate care quality and reduce risk with our technology, services, community, and expertise.
Notably, the Relias family of brands — Nurse.com, Wound Care Education Institute, Relias Academy, FreeCME, and Relias Media — serves the entire healthcare community. Designed to address the entire workforce journey, Relias’ solutions span healthcare and human service worker needs from recruiting and onboarding to career and performance development to working in a compliant and safe environment.
11. Moderna
Category: Biotech
In just over a decade since its inception, Moderna has transformed significantly. Starting as a company focused on messenger RNA (mRNA) technology, it has evolved into an enterprise. Moderna now has a clinical portfolio spanning seven therapeutic modalities, an intellectual property presence encompassing mRNA and lipid nanoparticle formulation, and an integrated manufacturing facility capable of production for both clinical and commercial purposes. Notably, the company’s work culminated in the development and authorization of one of the earliest COVID-19 vaccines during the global pandemic.
Moderna’s dedication to innovation has earned it recognition as a top biopharmaceutical employer by Science for eight consecutive years. With its headquarters in Cambridge, Massachusetts, and a workforce exceeding 6,000 employees, Moderna continues to pioneer advances in mRNA technology, making contributions to healthcare and science. Recently, it received FDA approval for an updated COVID-19 vaccine, underscoring its commitment to addressing global health challenges.
12. ConcertAI
Category: Software & Data
ConcertAI, headquartered in Cambridge, Massachusetts, with approximately 700 employees, stands as a global leader in Real-World Evidence (RWE) and AI technology solutions for the life sciences and healthcare sectors. Their mission revolves around the swift acceleration of insights and outcomes for patients. This mission is achieved through the application of leading-edge real-world data, AI technologies, and scientific expertise, all accomplished in close collaboration with premier biomedical innovators, healthcare providers, and medical societies.
In 2019, ConcertAI made significant strides in the healthcare arena. They expanded their data science collaboration with Janssen, focusing on driving effective therapies and addressing health disparities within clinical trials. Furthermore, a strategic agreement with Bristol-Myers Squibb was announced, aiming to broaden the utilization of Real-World Evidence and expedite precision oncology innovations. ConcertAI's partnership with Pfizer in the field of precision oncology showcases their commitment to accelerating patient insights and outcomes studies through the integration of Real-World Data and advanced AI capabilities.
13. Symplr
Category: Software & Data
Symplr is a leader in enterprise healthcare operations software and services. For more than 30 years and with solutions in 9 of 10 U.S. hospitals, Symplr has been committed to improving healthcare operations through its cloud-based solutions, driving better operations for better outcomes. Symplr’s data management, workforce management, and healthcare governance, risk management, and compliance (GRC) solutions improve the efficiency and efficacy of healthcare operations, enabling caregivers to quickly handle administrative tasks so they have more time to do what they do best: provide high-quality patient care.
In 2022, Symplr partnered with Daxtra Technologies to deliver solutions for healthcare staffing challenges. Symplr also expanded its Golf Sponsorship Program and welcomed PGA Tour Winner Sepp Straka. Additionally, Visier announced a strategic partnership with Symplr, signaling transformative developments in the field. Symplr's dedication to healthcare operational excellence continues to shape the industry's future.
14. Dexcom
Category: Medical Devices
DexCom, based in San Diego, California, pioneers continuous glucose monitoring (CGM) systems for diabetes management. Founded in 1999 and listed as NASDAQ: DXCM, the company develops and markets CGM systems for individuals with diabetes and healthcare providers. Dexcom prioritizes user and healthcare professional feedback, simplifying global diabetes management. With a workforce of over 8,000, the company has offices across the U.S., Europe, and Asia Pacific.
Recently, Dexcom received Health Canada approval for Dexcom G7, a next-generation Continuous Glucose Monitoring System known for its accuracy. Dexcom also showcased its CGM portfolio's precision, simplicity, and connectivity at the ATTD Conference, contributing to global CGM access expansion. Dexcom's dedication to improving diabetes care underscores its role in transforming the field.
15. Alto Pharmacy
Category: Consumer HealthTech
Alto is transforming a $500 billion industry by unlocking potential at every step of the prescription process. From the software in the doctor’s office, through benefits and price investigation, to hand-delivery to people’s homes and ongoing patient support, Alto’s platform delivers a level of value and care far beyond people’s expectations of traditional retail or digital pharmacies. Alto Pharmacy was started in 2015 by two Facebook engineers, Jamie Karraker and Mattieu Gamache-Asselin, who were frustrated with the existing pharmacy experience, how bad it was, and especially how little technology was being used within these systems. The San Francisco-based company began in the storage closet of a small independent pharmacy.
As of 2022, Alto has increased its reach to 13 markets, grown revenue to almost a billion dollars, and launched shopping for over-the-counter medications on their app. They also announced a new CEO joining September 1, Alicia Boler Davis. She joins Alto from Amazon, where she led global customer fulfillment, Amazon’s largest team, and previously General Motors, where she led global manufacturing, among many other teams. Alto has raised a total of $550 million from investors like Softbank Vision Fund, Greenoaks Capital, Jackson Square Ventures, and Olive Tree Capital.
16. Enovis
Category: Medical Device
With over 40 years in the industry and a focus on continuous improvement, Enovis™ is one of the world’s leading medtech companies with more than 1,000 total medical devices and 1,200 patents held. Enovis also covers the full orthopedic care continuum including performance, prevention, surgical, recovery, and rehabilitation. Built upon the strong orthopedic foundation of DJO® and the successful legacy of continuous improvement of Colfax®, the company has brought to life market-leading brands like DonJoy®, Aircast®, EMPOWR®, MotionMD®, and Companion Animal Health™. Enovis has more than 7,000 employees within 30 facilities worldwide and is headquartered in Wilmington, Del.
Enovis is an innovation-driven medical technology growth company. Together with clinicians, the company is creating the future of better care with its clinically differentiated solutions, helping healthcare professionals thrive and patients achieve extraordinary results. Powered by a culture of continuous improvement, global talent, and innovation, the Company’s extensive range of products, services, and integrated technologies fuels active lifestyles in orthopedics and beyond.
17. Amgen
Category: Biotech
Amgen is a global biotechnology company dedicated to science and innovation in medicine. They focus on translating discoveries into medications for patients with serious illnesses. Amgen uses advanced human genetics to understand disease and human biology, aiming to develop differentiated medicines that provide clinical benefits and reduce the societal and economic burdens of disease. The company's concentration is on high unmet medical needs, leveraging their expertise to improve health outcomes.
Since its inception in 1980, Amgen has become a leading independent biotechnology firm, impacting numerous patients worldwide and continually advancing its pipeline of medicines. Recent milestones include FDA approval for BLINCYTO® in treating minimal residual disease-positive B-cell precursor acute lymphoblastic leukemia, a collaboration with TSCAN Therapeutics to explore novel Crohn's disease targets, and compelling data from PROLIA® demonstrating a significant reduction in osteoporotic fracture risk compared to alendronate.
18. DispatchHealth
Category: Consumer HealthTech
On track to generate more than $2 billion in medical cost savings by 2023, DispatchHealth is pioneering an industry-wide shift in where healthcare is delivered, putting the well-being of patients at the forefront. By proving the viability of delivering the power of a hospital to patients at home and high-quality outcomes met with unprecedented patient satisfaction, the organization is bringing tech-enabled home-based medical care to the next level and moving the industry forward. Founded in 2013, DispatchHealth is the first to apply fully integrated 21st-century technology to the age-old concept of medical house calls – and the first platform of its kind to create a sustainable reimbursement model for high acuity care widely recognized by insurance companies.
In March 2021, DispatchHealth solidified its healthtech unicorn status with $200 million in Series D financing and a valuation of over $1.7 billion. The healthcare provider currently operates in 34 states with 60 distinct markets, including mobile diagnostics, and demand for a complete system of care in the home continues to climb. DispatchHealth is partnered with industry powerhouses to expand access to exceptional healthcare to as many people as possible––and they’re just getting started.
19. Pfizer
Category: Biotech
Pfizer, a leading research-based biopharmaceutical company headquartered in New York, NY, is dedicated to advancing global healthcare through innovation. With approximately 80,000 employees spread across more than 185 countries, Pfizer boasts an impressive annual revenue of around $31 billion and maintains 36 manufacturing sites worldwide. Pfizer's core mission is to improve lives by pushing the boundaries of science, developing groundbreaking therapies, and setting industry standards for quality, safety, and value in healthcare product discovery and production.
Recent achievements include U.S. FDA approval for their 2023-2024 COVID-19 vaccine in partnership with BioNTech, as well as European Commission approval for ABRYSVO™, protecting infants and older adults from RSV. Their partnership with esteemed foundations like the Bill & Melinda Gates Foundation and the Children’s Investment Fund Foundation underscores their commitment to expanding healthcare access, especially for women in low- and lower-middle-income countries. With over 170 years of transformative impact, Pfizer continues to lead the way in biopharmaceutical innovation, making a profound difference in healthcare worldwide.
20. Ascom
Category: Software and Data
The vision of Ascom is to close digital information gaps allowing for the best possible decisions – anytime and anywhere. The company provides mission-critical, real-time solutions for highly mobile, ad hoc, and time-sensitive environments. Ascom uses its standards based and scalable software architecture combined with its product and solutions portfolio to provide integration and mobilization solutions that deliver complete and efficient workflows with proven ROI for healthcare and enterprise environments.
Ascom has a strong global market presence and a loyal installed base of highly visible customers. With solid and proven products, technologies and service capabilities along with great talent and expertise in workflow technology Ascom is well positioned to be a global leader and solution provider in the healthcare ICT, industry, retail and security markets worldwide.
In North America, Ascom Americas has served more than 3,000 acute and long-term care facilities through a network of more than 150 sales partners with more than 3,000 certified technicians. Ascom Americas has provided more than 1,000 nurse call system installations and has more than 400 enterprise customers across industry verticals.
21. Innovent Biologics
Category: Biotech
Established in 2011, Innovent is a pharmaceutical company focused on developing, manufacturing, and commercializing innovative medicines for major diseases like cancer. Innovent, which is a publicly listed entity on the Main Board of the Stock Exchange of Hong Kong Limited, has developed a multi-functional platform that includes R&D, CMC (Chemistry, Manufacturing, and Controls), clinical development, and commercialization capabilities. With this platform, the company has built a pipeline of 23 assets in cancer, metabolic, autoimmune diseases, and other therapeutic areas, with four products officially approved for marketing in China, five assets in Phase III or pivotal clinical trials, and 14 molecules in clinical trials.
Innovent operates a biopharmaceutical production facility meeting global standards. Headquartered in Suzhou, Jiangsu, with around 800 employees, Innovent has entered into strategic cooperation with Eli Lilly, Adimab, Incyte, Hanmi, and other international pharmaceutical companies. Innovent recently received NMPA approval for SINTBILO® (Tafolecimab Injection) and FUCASO®, the first fully-human BCMA CAR-T therapy. They have also collaborated with RemeGen on combination therapy for advanced solid tumors.
22. Spring Health
Category: Software and Data
Spring Health, based in New York City, is a pioneer in reshaping mental health care. Their Precision Mental Health Care model, driven by data and AI, revolutionizes the industry, offering faster, higher-quality, and cost-effective care. The company's dedication to prioritizing members' needs drives innovation in every aspect of its operations. Spring Health collaborates with employers to modernize behavioral health benefits, offering a comprehensive solution for employee mental well-being. They serve as a central hub for various care options, including digital exercises, EAP services, coaching, therapy, and medication. Using proprietary assessment and machine-learning technology, they evaluate individual conditions, crafting personalized care plans.
Spring Health recently earned validation as the exclusive mental health solution delivering net savings to customers, reinforcing its commitment to efficiency. Furthermore, their expansion into Family Care and personalized support for children underscores their dedication to holistic well-being. Spring Health's innovative and individualized approach, coupled with a seamless member experience, solidifies its position as the premier behavioral health benefit provider, championing the mental health of contemporary individuals. With approximately 1,600 employees, Spring Health is at the forefront of shaping the future of mental healthcare.
23. Zynex Medical
Category: Medical Devices
Zynex, Inc. is an innovative medical technology company specializing in the manufacture and sale of non-invasive medical devices for pain management, rehabilitation, and patient monitoring. Zynex Inc. was founded by Thomas Sandgaard in 1996 and saw its first product cleared by the FDA in 1998. Zynex is located in Englewood, Colorado. From 2018 through 2021, its gross revenue has grown 308%.
The company operates through two divisions: Zynex Medical and Zynex Monitoring Solutions. Zynex Medical is focused on providing alternative pain management devices to patients across the nation. These pain management devices are electrotherapy, bracing, hot/cold therapy, and cervical traction. These devices are primarily used in rehabilitation or orthopedic settings. Zynex Monitoring Solutions is focused on developing non-invasive fluid, sepsis, and laser-based pulse oximetry monitoring systems for use in hospitals. Zynex Monitoring Solutions was founded in 2010 and had its first device cleared in 2020.
24. Sanofi
Category: Biotech
Sanofi, a leading global healthcare company headquartered in Paris, France, is at the forefront of medical innovation. With a presence in over 100 countries and a team of 80,000 dedicated professionals, Sanofi relentlessly pursues scientific breakthroughs to enhance the well-being of individuals worldwide. Sanofi's mission revolves around harnessing the power of science to create miracles that improve lives. They provide life-changing treatment options and life-saving vaccines, contributing significantly to global healthcare.
Recently, Sanofi has collaborated with organizations like the Meningitis Research Foundation and the Confederation of Meningitis Organisations to launch The Meningitis Flag, a global initiative aimed at raising awareness about meningitis. Additionally, the unanimous recommendation by the U.S. CDC Advisory Committee for the routine use of Sanofi's Beyfortus™ (nirsevimab-alip) to protect infants against RSV disease underscores their dedication to public health. Furthermore, Sanofi's strategic move to acquire Qunol®, a prominent U.S. brand in the healthy aging segment, demonstrates their commitment to expanding their impact and reach in the healthcare industry.
25. Nextech
Category: Software and Data
Nextech is the complete healthcare technology solution for specialty providers. Since 1997, Nextech has been focused on delivering innovative solutions and services that drive efficiency, fuel growth, and enhance the patient care experience. Nextech services more than 16,000 physicians and over 60,000 office staff members in the clinical specialties of Dermatology, Ophthalmology, Orthopedics, Plastic Surgery, and Med Spa.
26. Kimia Farma
Category: Biotech
Kimia Farma, founded in 1817 as NV Chemicalien Handle Rathkamp & Co. by the Dutch Indies Government, holds the distinction of being Indonesia's inaugural pharmaceutical industry company. Over the years, it has undergone significant transformations to become a prominent player in the nation's healthcare landscape. In 1958, as part of the post-independence nationalization policy, the Government of the Republic of Indonesia merged multiple pharmaceutical firms into PNF Bhinneka Kimia Farma.
Subsequently, on August 16, 1971, it transitioned from a state-owned entity to a Limited Liability Company, adopting the name PT Kimia Farma (Persero). Furthermore, a pivotal moment occurred on July 4, 2001, when PT Kimia Farma (Persero) transitioned to a public company, PT Kimia Farma (Persero) Tbk, and was listed on the Jakarta Stock Exchange and Surabaya Stock Exchange (now merged into the Indonesia Stock Exchange). Kimia Farma's headquarters are in Jakarta, Jakarta Pusat, and it boasts a dedicated workforce of approximately 3,000 employees.
27. Loftware
Category: Software and Data
Loftware is a cloud-based Enterprise Labeling and Artwork Management provider with a global presence, including offices in the US, UK, Germany, Slovenia, China, and Singapore. With over 35 years of experience, Loftware focuses on solving labeling challenges. As a global provider of Enterprise Labeling and Artwork Management, Clinical Trials Labeling, and Regulated Content Management, Loftware supports various industries such as automotive, chemicals, consumer products, electronics, food & beverage, manufacturing, medical device, pharmaceuticals, retail, and apparel.
Recent collaborations highlight Loftware's commitment to innovation. They've partnered with Tenthpin to endorse and implement the Loftware Prisym 360 software for clinical supply labeling, and they've also joined forces with Epson to transform labeling workflows, solidifying their industry leadership. Headquartered in Portsmouth, NH, Loftware has approximately 400 employees.
28. Cencora (formerly AmerisourceBergen)
Category: Biotech
Cencora, formerly AmerisourceBergen, is a global pharmaceutical solutions organization headquartered in Conshohocken, PA, with a team of over 46,000 professionals. Committed to enhancing the well-being of people and animals worldwide, Cencora collaborates with pharmaceutical innovators throughout the value chain to optimize market access for therapies. At its core, Cencora focuses on the secure and dependable delivery of pharmaceuticals, healthcare products, and solutions trusted by care providers.
The company's transformation into Cencora represents a unifying moment, rallying its vast workforce under a singular banner with a common purpose: to shape healthier futures. Cencora's philanthropic initiatives include a scholarship program supporting future Black and African American pharmacists in partnership with the AmerisourceBergen Foundation. Additionally, Cencora collaborates with Krystal Biotech to commercialize gene therapy.
29. Exact Sciences
Category: Biotech
Exact Sciences, headquartered in Madison, Wisconsin, is a prominent company at the forefront of cancer screening and diagnostics. With a workforce of 5,000 dedicated professionals, the company is committed to providing patients and healthcare practitioners with the essential clarity required to initiate life-altering decisions at an earlier stage. Notably, Exact Sciences has achieved considerable success with its renowned Cologuard® and Oncotype® tests.
The company’s groundbreaking diagnostic solutions have paved the way for the company's ongoing investment in an innovative pipeline. In recent developments, Exact Sciences demonstrated its commitment to growth and innovation by announcing a Debt Exchange Transaction and Private Placement of Convertible Senior Notes. Furthermore, the company launched the OncoExTra™ Cancer Therapy Selection Test in the United States, underscoring its dedication to advancing cancer diagnostics and treatment selection.
30. Tempus
Category: Biotech
With a stated mission of bringing the frontiers of technology to the world of medicine, Chicago-based biotech research company Tempus is leveraging an incredible data library to apply AI to the establishment of a new era of precision medicine. Tempus’ offerings empower healthcare partners to more efficiently diagnose patients and model the effectiveness of treatments, and its clinical trial matching capabilities have helped more than 10,000 patients since its founding in 2015.
Tempus is empowered to make use of its greater than 50 petabytes of data thanks to its partnerships with prominent figures across the biotech research world, including 120 biopharma companies and more than half of all academic medical centers in the U.S. As a recognized innovation driver in the industry, the company has announced recent advances in machine learning-based genomic testing, and has presented dozens of papers at this year’s meetings of the American Association for Cancer Research and the American Society of Clinical Oncology.
31. Syngene
Category: Biotech
Syngene International Ltd. is an integrated research, development, and manufacturing services company serving the global pharmaceutical, biotechnology, nutrition, animal health, consumer goods, and specialty chemical sectors. Syngene's 6,000 scientists offer both skills and the capacity to deliver science, data security, and manufacturing, improving time-to-market and lowering the cost of innovation. Headquartered in Bengaluru, Karnataka, with 7,000 employees, Syngene recently expanded operations in Genome Valley, Hyderabad.
With dedicated research facilities for Amgen, Baxter, and Bristol-Myers Squibb, along with 2 million square feet of specialist discovery, development, and manufacturing facilities, Syngene works with biotech companies and multinationals, including GSK, Zoetis, and Merck KGaA. Panbela announces issuance of a new patent in Australia for a novel process for the production of SBP-101. Syngene is set to acquire a multi-modal facility from Stelis Biopharma Ltd.
32. AstraZeneca
Category: Biotech
AstraZeneca, a leading global biopharmaceutical company headquartered in Cambridge, UK, is dedicated to advancing science and improving global healthcare. With a presence in over 100 countries and a workforce of approximately 60,000 employees, AstraZeneca is at the forefront of innovation in the field of prescription medicines. The company's primary areas of focus include Oncology, Rare Diseases, and BioPharmaceuticals, encompassing Cardiovascular, Renal & Metabolism, and Respiratory & Immunology.
AstraZeneca's commitment to research and development has led to the creation of groundbreaking medicines that benefit millions of patients worldwide. In recent developments, AstraZeneca achieved significant milestones with the approval of its products. Calquence received approval in China for the treatment of chronic lymphocytic leukaemia, while Soliris gained approval in Japan for paediatric patients with generalised myasthenia gravis (gMG). Additionally, Lynparza, in combination with abiraterone, was approved in Japan for the treatment of BRCA-mutated metastatic castration-resistant prostate cancer.
33. Demant A/S
Category: Medical Devices
Demant is a leading global hearing healthcare group focused on enabling individuals with hearing loss to connect and communicate effectively with the world. With a rich history spanning over a century, the Demant Group has been at the forefront of pioneering technologies and expertise to enhance auditory health. Their extensive range includes hearing devices, implants, diagnostic equipment, and hearing care services, serving a global clientele. Operating in more than 30 countries and boasting a workforce of around 20,000 employees, Demant achieves an annual revenue of approximately DKK 18 billion.
The company’s life-changing hearing health solutions reach over 130 countries, making a significant impact. Demant is prominently listed on the Nasdaq Copenhagen stock exchange, featured as part of the C25 index, demonstrating its financial significance. The company is the parent organization behind renowned brands such as Oticon, Bernafon, Sonic, Audika, Oticon Medical, MAICO, Interacoustics, Amplivox, Grason-Stadler, MedRx, and EPOS. Majority-owned by William Demant Invest A/S, an entity of the William Demant Foundation, Demant enjoys long-term stability and resilience. Demant remains a driving force in hearing healthcare and intelligent audio solutions.
34. PTC Therapeutics
Category: Biotech
PTC is a global biopharmaceutical company with a 25-year history of developing therapies for rare diseases. Headquartered in South Plainfield, NJ, and employing over 1,000 professionals, PTC is committed to addressing the root causes of these ailments, ultimately enhancing the quality of life for patients who depend on their innovations. Specializing in the discovery, development, and commercialization of medicines tailored for rare disorders, PTC sets itself apart through its ability to continually innovate. This innovation is evident in their robust pipeline of medicines, demonstrating their dedication to delivering treatments. PTC's mission centers on granting access to therapies for patients facing limited or nonexistent treatment options, ensuring the well-being of all stakeholders.
Notably, PTC Therapeutics recently made strides in its commitment to the Duchenne patient community through the 2023 STRIVE Awards Program. Additionally, the company unveiled promising results from the Vatiquinone MOVE-FA Registration-Directed Trial. PTC's unwavering dedication to scientific excellence and global reach positions it at the forefront of the biopharmaceutical industry, providing hope and solutions for those in need.
35. Healthmap Solutions
Category: Software and Data
Healthmap Solutions, an NCQA-accredited Kidney Population Health Management company, is dedicated to enhancing the lives of individuals with chronic kidney disease across the United States. With a headquarters located in Tampa, FL, and a workforce exceeding 300 employees, Healthmap Solutions is at the forefront of transforming kidney care. Healthmap leverages cutting-edge predictive analytics technology and clinical expertise to identify kidney disease in its early stages. This proactive approach allows them to recommend evidence-based interventions that can slow or delay disease progression.
Moreover, Healthmap Care Navigation teams collaborate closely with patients and a wide range of healthcare providers within health plans. One of Healthmap's primary focuses is on optimizing renal replacement therapy, with an emphasis on in-home dialysis treatment and transplant options. This approach not only improves the quality of care and patient experience but also significantly reduces overall medical costs for health plans and provider groups.
36. Biocytogen
Category: Biotech
Biocytogen is a global biotechnology company focused on antibody-based drug development. They utilize their RenMabTM, RenLite®, and RenNano® mice platforms to create human monoclonal antibodies, bispecific/multispecific antibodies, and nanobodies. These platforms are integrated with in vivo drug efficacy screening and clinical development expertise to streamline drug development. Project Integrum (RenMiceTM HiTS Platform) is a large-scale effort targeting over 1000 antibody drug candidates.
Biocytogen has established 50 therapeutic antibody co-development, out-licensing, and transfer agreements, along with 42 target-nominated RenMiceTM licensing projects globally, including partnerships with multinational pharmaceutical companies. Biocytogen's pipeline comprises 10 core assets, developed in collaboration with partners. Headquartered in Beijing, they have branches in Haimen Jiangsu and Shanghai (China), Boston and San Francisco (USA), and Heidelberg (Germany).
37. PartsSource
Category: Software and Data
PartsSource is the leading evidence-based B2B vertical marketplace and supply chain software platform used by the healthcare provider and supplier ecosystem to improve essential clinical operations, staff productivity, costs, asset uptime and supply chain resiliency. Today they help more than 5,000 member hospitals and more than 15,000 clinical sites achieve sustainable savings and efficiencies.
As healthcare’s leading source of knowledge, processes and components, PartsSource can transform their clients’ supply chain, improve the way their clients work, and ensure healthcare is always available. In addition to automating the highly complex workflow associated with procurement and vendor management, their team can work with clients to identify new opportunities for efficiencies and improved availability.
38. Alphatec Spine
Category: Medical Devices
ATEC, headquartered in Carlsbad, CA, is not your typical medical technology company. It operates as an Organic Innovation Machine™ with an unwavering commitment to Revolutionizing the Approach to Spine Surgery. Through its subsidiaries, Alphatec Spine, Inc., EOS imaging S.A.S., and SafeOp Surgical, Inc., ATEC stands as a medical device industry pioneer, dedicated to reshaping spine surgery through clinical distinction. ATEC's innovative spirit is encapsulated in its vision—to become The Standard-Bearer in Spine. By relentlessly pursuing superior outcomes, this company transforms lives with groundbreaking spine surgery solutions.
ATEC collaborates closely with spine surgeons to design and develop cutting-edge products and systems that enhance the entire spinal fusion procedure. Recent developments include a notable $60 million underwritten offering and the acquisition of a Navigation-Enabled Robotics Platform. These strategic moves, bolstered by robust preliminary first-quarter revenue results, have propelled ATEC to raise its 2023 revenue guidance. With approximately 900 dedicated employees, ATEC's journey to redefine spine surgery continues, guided by a steadfast commitment to innovation and clinical excellence.
39. Bluebird Bio
Category: Biotech
Bluebird Bio, headquartered in Somerville, MA, is a pioneering company dedicated to revolutionizing the treatment of severe genetic diseases through curative gene therapies. Founded in 2010, the company has emerged as an industry leader with a profound commitment to improving the lives of patients and their families by providing them with more "bluebird days." Bluebird bio's primary focus lies in severe genetic diseases, with groundbreaking programs addressing conditions such as sickle cell disease, β-thalassemia, and cerebral adrenoleukodystrophy.
What sets Bluebird apart is its meticulous approach—each therapy is custom-designed to target the root cause of the disease. The company has also developed state-of-the-art analytical methods to ensure the safety of its lentiviral vector technologies, driving the gene therapy field forward. With the largest and most comprehensive ex-vivo gene therapy dataset globally, Bluebird Bio sets the industry standard. Their dedication extends beyond innovation, fostering a people-centric culture that attracts and nurtures a diverse workforce of dedicated individuals. With around 500 employees, Bluebird Bio is actively shaping the future of gene therapy, leveraging its real-world experience and unwavering commitment to patient communities.
40. ImmunoGen
Category: Biotech
ImmunoGen, headquartered in Waltham, Massachusetts, pioneers antibody-drug conjugates (ADCs) for cancer treatment, aiming to enhance patient lives. With a commitment to "TARGET A BETTER NOW™," the company is dedicated to improving cancer outcomes. Their leading product, mirvetuximab soravtansine, is a groundbreaking ADC targeting folate receptor alpha (FRα), with ongoing studies in ovarian cancer. Their second pivotal program, IMGN632, targets CD123 and is being investigated as both a monotherapy in BPDCN and in combination for AML.
With approximately 300 employees, ImmunoGen continues to innovate and expand its global presence. Recently, the company announced a collaboration with Takeda to develop and commercialize ELAHERE® in Japan, further advancing their mission to provide cutting-edge cancer therapies worldwide. ImmunoGen's commitment to "targeting a better now" is changing the landscape of cancer treatment.
41. Viz.ai
Category: Software and Data
Viz.ai, headquartered in San Francisco, CA, is a pioneer in the application of AI algorithms and machine learning to healthcare. With a reach extending to over 220 million individuals across 1,400+ healthcare facilities in the United States and Europe, the company is at the forefront of enhancing the speed and quality of medical diagnosis and treatment. At the core of Viz.ai's innovation is the AI-powered Viz Platform, an intelligent care coordination solution designed to swiftly identify patients with suspected diseases, facilitate critical decisions at the point of care, and optimize treatment pathways for improved outcomes.
Recent developments underscore Viz.ai's commitment to advancing healthcare. The company has entered into a license agreement with UCSF to commercialize three cardiac artificial intelligence algorithms, reinforcing their dedication to research and technology. Additionally, Viz.ai has launched the Viz™ Trauma Suite, aligning with evolving trauma center standards. Notably, Viz.ai achieved a milestone as the first recipient of FDA 510(k) clearance for an AI algorithm aimed at abdominal aortic aneurysm, reaffirming their position as a trailblazer in healthcare innovation.
42. LetsGetChecked
Category: Consumer HealthTech
LetsGetChecked, a global healthcare solutions company, enables individuals to manage their health from the comfort of their homes. They offer direct access to diagnostic testing, virtual care, and medication delivery for a wide range of health and wellness concerns. LetsGetChecked's comprehensive approach covers the entire healthcare journey, including manufacturing, logistics, lab analysis, physician support, and prescription fulfillment. The company's mission is to empower people with easy access to health information and care, fostering longer and happier lives.
LetsGetChecked operates nationwide in the United States, the United Kingdom, and most EU countries. It is co-headquartered in Dublin and New York, with an employee base of approximately 800 and a substantial clientele of 300 corporate partners. In 2022, LetsGetChecked made significant strides in the field of personalized at-home healthcare by acquiring Veritas Genetics and Veritas Intercontinental. They also introduced the CarePathway™, a comprehensive 360-degree customer care program, and expanded their COVID-19 offerings with antigen testing and virtual observation services, demonstrating their commitment to safeguarding the health and wellbeing of employees.
43. Maven Clinic
Category: Consumer HealthTech
Maven is the world's largest virtual clinic specializing in women's and family health, offering comprehensive care from fertility to menopause, catering to maternity, parenting, pediatrics, and beyond. Maven's exceptional digital solutions have earned trust among leading employers and health plans, yielding cost reductions, improved maternal health, and diversity, equity, and inclusion (DE&I) enhancements in benefits programs. The company believes in the continuous journey towards greater inclusion and is dedicated to evolving alongside its community.
Founded in 2014 by CEO Kate Ryder, Maven has emerged as a beacon of innovation in healthcare. It has secured $300 million in funding from notable investors, including General Catalyst, Sequoia, Oak HC/FT, Dragoneer Investment Group, and Lux Capital. Recognized as Fast Company's #1 Most Innovative Health Company, Maven's reach extends to 15 million individuals globally. Notably, recent partnerships with Amazon and the acquisition of Naytal underscore Maven's commitment to expanding its services and promoting accessible healthcare on a global scale.
44. Rocket Pharmaceuticals
Category: Biotech
Rocket Pharmaceuticals pioneers turning innovative science into potential gene therapy cures by advancing a multi-platform approach and world-class pipeline of first-of-their-kind therapies for the betterment of our industry, science and humanity. Headquartered in New Jersey with nearly 300 employees, Rocket is a leading late-stage biotechnology company advancing an integrated and sustainable pipeline of genetic therapies for rare disorders with high unmet need.
Since its inception in late 2015, Rocket has been tirelessly working to bring gene therapies to patients with rare diseases. The company is advancing a world-class pipeline of six programs across both AAV and LV platforms to address life threatening cardiac and hematologic rare diseases. Most recently, Rocket's Biologics License Application (BLA) for its LV-based gene therapy for severe Leukocyte Adhesion Deficiency-I (LAD-I) was accepted and granted priority review by the FDA. Rocket also reached FDA alignment on its pivotal Phase 2 trial design for its gene therapy in Danon Disease. The company has received FDA Fast Track and Orphan Drug Designations across five of its programs, and EMA Priority Medicines (PRIME) and FDA Regenerative Medicine Advanced Therapy (RMAT) Designations across four of its programs.
These therapies represent a paradigm shift in healthcare, offering hope for patients with rare and devastating conditions who often have inadequate treatment options and providing insights for the scientific community that may be applied to other conditions.
45. BrightInsight
Category: Software and Data
BrightInsight, founded in 2017, provides the leading global platform for compliant biopharma and medtech digital health solutions, helping companies accelerate time-to-market for digital health offerings across therapeutic areas, including drug companion apps, healthcare provider interfaces, analytics dashboards, algorithms, medical devices, connected combination products, diagnostics and Software as a Medical Device (SaMD).
BrightInsight replaces the need for complex 'build from scratch' implementations by offering configurable software solutions and a proven platform built on Google Cloud under a Quality Management System to support global security, privacy, and regulatory requirements. Since initially launching the BrightInsight Platform in 2018, the company has invested over $100M in its underlying infrastructure – which allows it to deliver industry-leading scalability, functionality, configurability, speed, compliance and global availability.
BrightInsight partners with leading global biopharma and medtech companies including CSL Behring, Roche and bioMérieux and its platform is available across 64 geographies.
46. MegaRobo
Category: Software and Data
Founded in 2016, MEGAROBO is a science and technology company specializing in providing productivity tools for life sciences, clinical diagnostics, and applied chemistry industries. MEGAROBO leverages robotic automation and AI technologies to accelerate productivity and innovation, aiming to engineer a more efficient world. Their self-developed intelligent biological laboratory, MegaLab, enhances automation in new drug discovery, cell and gene therapy, organoids, and synthetic biology, ultimately improving human health.
MEGAROBO values independent development and technological innovation, with over 60% of its team dedicated to R&D. The company has filed nearly 600 patents and has a global presence with sites in Beijing, Shanghai, Shenzhen, Suzhou, the United States, the United Kingdom, and Japan. Recently, MEGAROBO closed its Series C financing round with key investors including WuXi AppTec, Bosch, Sino Biological, Goldman Sachs Asset Management, Asia Investment Capital, Sinovation Ventures, Joy Capital, Matrix Partners China, and Pavilion Capital, solidifying its position as a driving force in the life sciences automation sector.
47. Meril Life
Category: Medical Devices
Founded in 2006, Meril is a globally recognized medical device company based in India. The company, established by the Bilakhia Group, is driven by an unwavering commitment to improving human lives through cutting-edge healthcare solutions. Meril's primary focus is on research and development, innovation in medical technology manufacturing, scientific communication, and modern distribution methods. With a mission to alleviate human suffering and enhance quality of life, Meril manufactures a wide range of medical solutions, including vascular intervention devices, orthopaedic supplements, in-vitro diagnostics, endo-surgery, and ENT products.
Meril actively collaborates with healthcare professionals and global innovators to identify unmet clinical needs and develop groundbreaking therapies. Through research and academic partnerships, they remain at the forefront of medical advancements. Headquartered in India and employing over 4000 individuals, Meril operates in more than 100 countries worldwide. The company boasts 100% subsidiaries in key regions, including the USA, Germany, Brazil, Russia, South Africa, Bangladesh, and Turkey, with expanding operations in China and Japan. Meril, powered by the Bilakhia Group, continues to lead the way in delivering innovative healthcare products to a global audience.
48. SprintRay
Category: Medical Devices
SprintRay is a dental technology company dedicated to providing comprehensive 3D printing solutions for dental professionals. They specialize in designing and manufacturing user-friendly, state-of-the-art dental products, including 3D printers, post-processing ecosystems, 3D printing software with AI technology, and innovative 3D resins. SprintRay's mission is to empower dental care providers with specialized and cost-effective technologies, enabling them to offer top-tier service to their patients.
In 2022, SprintRay introduced several notable innovations to their product lineup. One standout is the SprintRay Crown™ by BEGO, a groundbreaking development aimed at democratizing digital dentistry. This offering expands the Ceramic Crown Shades Portfolio, allowing dental professionals to 3D print crowns in various shades, including Bleach, C2, and D2. Furthermore, SprintRay launched ProWash S, a cutting-edge product that features Cloud Connectivity, streamlining the 3D printing workflow and making it more efficient for dental professionals.
49. Welldoc
Category: Consumer HealthTech
Welldoc® is a global digital health leader transforming healthcare with its comprehensive chronic care platform that integrates personalized, real-time and actionable insights into the daily lives of individuals, enabling improved health and outcomes. Welldoc’s scalable platform provides multi-condition support across pre-diabetes, diabetes, hypertension, heart failure, weight and obesity management, and mental wellbeing. Welldoc partners with health plans, health systems and employers with the goal of extending care, improving health and reducing costs.
Welldoc operates ahead of the curve of innovation in the digital health industry and continues to evolve and expand their offerings in line with market and consumer needs. This is possible through the company’s deep understanding of the healthcare ecosystem, specialized expertise in digital health for chronic care and flexible, partnership-based model and tech. The company’s foresight into industry needs enables Welldoc to deliver a best-in-class digital health solution, while ensuring seamless integration into existing health ecosystems.
50. TauRx Pharmaceuticals
Category: Biotech
The TauRx group of companies, established in 2002 in Singapore in partnership with the University of Aberdeen, has become a leader in Alzheimer's and neurodegenerative disease research. With its primary research facilities and operations based in Aberdeen, UK, TauRx has dedicated the past two decades to addressing the challenge of Alzheimer's and other neurodegenerative disorders linked to protein aggregation pathology. Positioned at the forefront of Alzheimer's research, the company is committed to uncovering, developing, and bringing innovative solutions for diagnosing, treating, and ultimately curing neurodegenerative conditions.
In a recent achievement, TauRx's hydromethylthionine mesylate (HMTM) demonstrated a significant reduction in neurodegeneration associated with Alzheimer's Disease (AD). This breakthrough was announced in 2022, accompanied by TauRx's announcement of an additional investment of USD 119 million, building on the Phase 3 LUCIDITY Topline Results. With its pioneering research and commitment to making a difference in the lives of those affected by neurodegenerative diseases, TauRx continues to be a beacon of hope in the quest to conquer Alzheimer's and related disorders.
51.Therabody
Category: Medical Devices
Therabody is a pioneer in wellness technology, focused on optimizing human performance and well-being. Founded by Dr. Jason Wersland, who invented the game-changing Theragun percussive therapy device after a personal traumatic accident, the company blends over a decade of research and development into its products. Therabody's mission revolves around empowering individuals worldwide to lead healthier lives through a deeper understanding of their bodies and minds. Their science-backed solutions encompass pneumatic compression (RecoveryAir), electrical stimulation (PowerDot), vibration therapy (Wave series), and USDA Certified Organic CBD (TheraOne).
Scientific rigor is fundamental to Therabody's approach. They use existing and original research to validate their products and services, earning trust within the medical community and among millions of consumers in 60+ countries. This trust extends to their company-owned retail stores and ResetⓇ wellness centers. Therabody's workplace culture is characterized by collaboration, innovation, and a forward-thinking mindset. They seek driven individuals inspired by the evolving landscape of health and well-being to join their team, fostering a collective effort to shape a healthier future.
52. Twist Bioscience
Category: Biotech
Twist Bioscience, based in South San Francisco, California, is a synthetic biology company specializing in a proprietary silicon-based manufacturing process for synthetic DNA production. With around 1,000 employees, Twist Bioscience serves diverse life science researchers spanning medicine, agriculture, industrial chemicals, and data storage. These scientists utilize Twist Bioscience's synthetic genes, oligo pools, and NGS target enrichment to advance their work, aiming to improve lives and enhance sustainability.
Their technology streamlines DNA synthesis and sequencing, ensuring cost-effective, rapid, and precise results, empowering researchers to seize opportunities. Recent developments include collaborations with Ono Pharmaceutical to explore antibodies for autoimmune diseases, the launch of an RNA Fusion Panel with CeGaT for oncology and precision medicine research, and a partnership with Aster Insights for the Next Generation Oncology Panel. Twist Bioscience has also expanded its portfolio with a range of RNA sequencing tools, reinforcing their commitment to scientific advancement.
53. Scientist.com
Category: Biotech
Scientist.com is a privately held, San Diego-based company on a mission to empower and connect scientists and make it faster and cheaper to discover new medicines. At its heart is an AI-powered marketplace for complex research experiments with the potential to transform the pharmaceutical industry in the same way Amazon has transformed the retail industry. Scientist.com’s clients include most of the world’s largest pharmaceutical companies, 100+ biotechs and the US National Institutes of Health. Through Scientist.com, these clients communicate directly with research experts at over 4,000 global laboratories to design and execute complex research experiments.
In 2023, Scientist.com was recognized by Fortune as America’s 11th Most Innovative Company. Scientist.com was recognized as the Overall BioPharma Solution of the Year in the 2022 BioTech Breakthrough Awards and was also named to Inc. magazine’s “Honor Roll'' for being one of the fastest-growing private companies in America five consecutive years, from 2017-2021, ranking as high as #9.
54. Outset Medical
Category: Medical Devices
Outset Medical, headquartered in San Jose, California, specializes in the Tablo console, a hemodialysis machine designed for versatile use in homes, clinics, nursing homes, hospitals, and intensive care units. Formerly known as Home Dialysis Plus, the company obtained its initial FDA 510(k) clearance for Tablo in 2014.
Recent developments highlight Outset Medical's commitment to advancing the field. They are set to present research findings that underscore the success of home hemodialysis, particularly for underserved populations, at the National Kidney Foundation Spring Clinical Meetings. This initiative reflects the company's dedication to improving access to hemodialysis solutions and enhancing patient outcomes.
55. Roivant Sciences
Category: Biotech
Sometimes the biomedical research that attracts the most attention from investors is disconnected from the greatest areas of societal need; for that reason, Roivant Sciences is dedicated to getting innovative treatment methods to the patients that need them. It is able to accomplish this goal by establishing subsidiary biotechnology and healthcare companies known as Vants, nimble entities that are able to quickly develop and deploy the latest breakthroughs to treat conditions such as Parkinson’s, diabetes, hypertension, and endometriosis.
Roivant was founded by Vivek Ramaswamy in 2014 with an eye toward incentivizing rapid deployment, and has successfully developed more than 40 critical drugs among its subsidiary divisions. Currently under development is a topical dermatitis medication by Dermavant, a biologic treatment for thyroid eye disease by Immunovant, and a solid tumor biologic by Affivant. The company was launched to great acclaim on the Nasdaq in late 2021, following a merger with Montes Archimedes Acquisition Corporation.
56. GeneDx (previously Sema4)
Category: Software & Data
GeneDx is a leader in delivering personalized health insights to drive diagnosis, treatment, and drug discovery. The company is positioned to utilize genomic and clinical data to enable precision medicine as the standard of care. GeneDx specializes in exome and genome testing and interpretation, supported by one of the world's largest rare disease data sets.
Recently, GeneDx has embarked on collaborations to enhance its mission. They have partnered with PacBio and the University of Washington for research on long-read whole genome sequencing in neonatal care, aiming to improve diagnostic yield. Additionally, GeneDx has joined forces with Prognos Health to expedite access to treatment options for rare disease patients, emphasizing their commitment to helping individuals with rare conditions explore therapeutic pathways.
57. Tomorrow Health
Category: Software and Data
Tomorrow Health is America’s leading home-based healthcare provider, using high-impact technology to transform the way care is ordered, delivered, and paid for. The company’s technology-driven matching process considers specialization, insurance coverage, geography, and more to pair patients with appropriate suppliers of more than 40,000 products and services.
One in four Americans today have a need for home-based care: from a new mother requiring a breast pump and an in-home lactation consultant, to a chronic COPD patient on oxygen relying on a CPAP machine. Tomorrow Health addresses these challenges with technology that connects providers, health plans, home-based care suppliers, and patients, tracking and managing every step of home-based care from prescription to billing.
58. Adaptive Biotechnologies
Category: Biotech
Adaptive Biotechnologies, headquartered in Seattle, WA, is a leader in the biotechnology sector, focused on harnessing the adaptive immune system for disease diagnosis and treatment. With around 700 employees, the company has established itself as a player in this field. At Adaptive Biotechnologies, they see the adaptive immune system as a powerful tool for disease management. Their immune medicine platform enables the decoding and translation of the genetics of the adaptive immune system. This capability empowers them to develop products within their Immune Medicine and Minimal Residual Disease (MRD) divisions.
Recent milestones include the launch of Epic Integration for clonoSEQ® and the FDA's acceptance of Genentech's Investigational New Drug Application for the First Neoantigen-Directed T-Cell Therapy Product in Oncology. Their collaboration with Takeda to measure Minimal Residual Disease with the clonoSEQ® Assay across its Hematologic Malignancy Pipeline underscores their dedication to advancing medical research and patient care.
59. Ascendis Pharma
Category: Biotech
Ascendis Pharma, a dynamic and innovative biopharma company, is on a mission to transform the lives of patients through groundbreaking therapies. With its pioneering TransCon technology platform, the company is at the forefront of biopharmaceutical advancements. Headquartered in Copenhagen, Denmark, Ascendis Pharma boasts a global presence with facilities in Germany and the United States. These strategic locations underscore the company's dedication to expanding its reach and impact on patients worldwide.
Recent achievements highlight Ascendis Pharma's commitment to innovation and patient care. The launch of SKYTROFA® in Germany, a once-weekly treatment for children and adolescents with Growth Hormone Deficiency, underscores the company's dedication to meeting unmet medical needs. Additionally, the positive CHMP opinion for TransCon™ PTH for adults with Chronic Hypoparathyroidism signifies the company's continuous drive to develop best-in-class therapies. Ascendis Pharma's partnership with Royalty Pharma, featuring a $150 million Royalty Funding Agreement, further demonstrates their commitment to advancing healthcare solutions.
60. Autolus
Category: Biotech
Autolus is a clinical-stage biopharmaceutical company developing T cell therapies for the treatment of cancer. Using a suite of proprietary T cell programming technologies, the Company engineers targeted and highly active T cell therapies to recognize cancer cells, break down their defense mechanisms, and eliminate them. Autolus has a pipeline of product candidates for hematological malignancies and solid tumors.
Autolus Therapeutics recently selected Cardinal Health as a U.S. commercial distribution partner. Autolus Therapeutics also announced a collaboration with Cabaletta Bio for the use of Autolus’ Safety Switch System in cell therapies for autoimmune disease. Headquartered in White City, London, with 400 employees, Autolus is dedicated to advancing cancer treatment through innovative T cell therapies.
61. ModuleMD
Category: EHR and Healthcare
ModuleMD is a leading physician-designed SaaS (Software-as-a-Service) provider. With over two decades of experience, ModuleMD offers specialty-specific workflows, Electronic Health Records, Practice Management software, Full Revenue Cycle Management services, and Patient Engagement. ModuleMD’s software provides flexibility and is designed to enhance clinical performance and increase efficiency and ROI for medical practices. The Company’s bi-directional partner integrations further enhance product offerings and improve overall practice workflow.
ModuleMD, an industry leader in the EHR SaaS market has been recognized as a High Performer in the EHR category by G2. ModuleMD's top classification comes from a 100% customer satisfaction score and high scores of 98% across various key performance indicators. As an ONC Certified EHR designed by physicians for physicians, ModuleMD’s attention to detail in SaaS user experience sets ModuleMD apart from its competitors.
62. BridgeBio Pharma
Category: Biotech
BridgeBio Pharma, Inc. is a pioneering commercial-stage biopharmaceutical company with a mission to revolutionize the field of medicine by discovering, creating, testing, and delivering groundbreaking therapies for patients afflicted by genetic diseases and cancers with well-defined genetic triggers. Founded in 2015, BridgeBio has swiftly emerged as a prominent player in the biopharmaceutical industry. Headquartered in Palo Alto, California, BridgeBio boasts a dedicated team of accomplished drug discoverers, developers, and innovators who share an unwavering commitment to harnessing the latest breakthroughs in genetic medicine.
In a recent landmark collaboration, BridgeBio Pharma has joined forces with Burjeel Holdings to launch the 'Nader' rare disease research and development project. With approximately 300 talented employees, BridgeBio Pharma, Inc. continues to be at the forefront of the biopharmaceutical sector, poised to make a significant impact in the lives of patients worldwide.
63. Centogene
Category: Software & Data
CENTOGENE is a company with a mission to transform healthcare for patients, physicians, and pharmaceutical companies dealing with rare and neurodegenerative diseases. Established in 2006, CENTOGENE has become a global leader in delivering rapid and dependable diagnoses, boasting a network of around 30,000 active physicians. The company's approach involves the integration of multiomic technologies with their CENTOGENE Biodatabank, a repository of medical data. This fusion empowers precision medicine by providing comprehensive dimensional analysis.
CENTOGENE's multiomic reference laboratories in Germany leverage a spectrum of datasets, including Phenomic, Genomic, Transcriptomic, Epigenomic, Proteomic, and Metabolomic information. This data is harnessed within the CENTOGENE Biodatabank, which contains records for over 800,000 patients from more than 120 countries, with a significant proportion representing non-European backgrounds. This resource has contributed to over 285 peer-reviewed publications. The company also collaborates with pharmaceutical companies to expedite drug discovery and development, including target and drug screening, clinical development, market access, and expansion.
64. Cerevel Therapeutics
Category: Biotech
Cerevel Therapeutics, based in Cambridge, Massachusetts, is dedicated to unraveling the brain's mysteries for neuroscience disease treatment. Established in late 2018 through a partnership with Pfizer and Bain Capital, Cerevel Therapeutics combines expertise in brain biology, neurocircuitry, chemistry, and CNS receptor pharmacology to discover therapies.
Their pipeline includes clinical-stage investigational therapies and preclinical compounds targeting neuroscience diseases like schizophrenia, Alzheimer's disease psychosis, epilepsy, panic disorder, and Parkinson's disease.
Beyond their research and development, Cerevel Therapeutics explores new avenues through internal research, external partnerships, and potential acquisitions. They efficiently leverage resources and capital by forming strategic alliances. With a seasoned team of leaders and neuroscience drug developers, Cerevel Therapeutics embodies a nimble, results-driven biotech mentality. They are poised to lead the charge in revolutionizing neuroscience research and treatment, offering hope to individuals worldwide.
65. RXNT
Category: Software & Data
RXNT is one of the most enduring pioneers in the ambulatory healthcare technology space, providing integrated, cloud-based software to thousands of physicians, healthcare providers, medical billers, and health organizations across the United States. Founded by Randy Boldyga in 1999, the company first reinvented the prescription process with an electronic prescribing solution, which still remains the industry standard today. Headquartered in Annapolis, Maryland, RXNT has positioned itself as a trusted and reliable partner in the healthcare industry.
They also provide solutions that align with regulatory requirements such as MIPS (Merit-based Incentive Payment System) and Meaningful Use. RXNT’s platform has enabled more than 100 million prescriptions transmitted, over 10 million signed encounters, and $300 million in yearly claims processed on average. With a team of more than 100 dedicated employees, RXNT has built a reputation for delivering cutting-edge technology that streamlines healthcare workflows, enhances patient care, and improves medical business processes.
66. Kontakt.io
Category: Software and Data
Headquartered in New York, Kontakt.io is the fastest-growing SaaS provider and a pioneer in Inpatient Journey Analytics that optimizes the efficiency and quality of care operations. By understanding how patients move through the care delivery process, Kontakt.io helps health systems uncover waste, improve workflows, and transform experiences for staff and patients. Using RTLS, IoT and AI, Kontakt.io delivers a cloud-based platform for over 30 use cases, including asset tracking, bed management, staff safety, patient flow, wayfinding, and much more.
Built on open-standard technologies, Kontakt.io has the most IT-friendly platform that can be rapidly deployed and easily integrated into existing network infrastructure, creating ROI within months of installation. Delivered as a service, its solutions span BLE sensors and tags, BLE gateways, web applications, and APIs, giving health systems a 360° view of the clinical spaces, assets, processes, and people. Since 2013, Kontakt.io has provided solutions to over 32,000 end users, delivered via +1,200 partners, and deployed +3 million IoT devices in the field.
67. Apixio
Category: Software and Data
Apixio is the Connected Care platform at the intersection of health plans and providers. Its AI technology and flexible services power risk adjustment, payment integrity, and care delivery programs using centralized patient health profiles, data-driven insights, and seamless workflows. Healthcare organizations can streamline operations, ensure accurate payment, and uncover critical patient insights—building a resilient foundation for success as the industry moves toward value-based reimbursement models.
68. CureVac
Category: Biotech
CureVac (Nasdaq: CVAC) is a global biopharmaceutical leader in messenger RNA (mRNA) technology, boasting over two decades of expertise in developing, optimizing, and manufacturing this versatile biological molecule for medical applications. Their pioneering proprietary technology harnesses optimized mRNA as a data carrier, instructing the body to produce disease-fighting proteins. Notably, CureVac partnered with GSK in July 2020, collaborating on innovative prophylactic vaccines for infectious diseases based on second-generation mRNA technology.
Headquartered in Tübingen, Baden-Württemberg, Germany, CureVac has 800 dedicated employees. Recent achievements include the successful closing of a $250 million Follow-on Public Offering of Common Shares, underlining their remarkable progress. CureVac's strategic vision extends to oncology, demonstrated by the acquisition of Frame Cancer Therapeutics in 2022, bolstering their cancer therapy portfolio. CureVac also partnered with myNEO to identify novel antigen targets, further advancing mRNA-based cancer vaccine development.
69. Deciphera Pharmaceuticals
Category: Biotech
Deciphera, headquartered in Waltham, Massachusetts, is a pioneering biopharmaceutical company dedicated to enhancing the well-being of individuals grappling with cancer. Leveraging their cutting-edge switch-control kinase inhibitor platform and profound knowledge of kinase biology, Deciphera is committed to bringing to market groundbreaking medicines. They have cultivated a diverse portfolio of inventive therapeutic candidates, with a particular focus on QINLOCK®—their switch-control inhibitor designed for fourth-line GIST treatment.
With a team of approximately 400 dedicated professionals, Deciphera remains at the forefront of cancer research and drug development. Their recent achievement in completing the enrollment for the pivotal Phase 3 MOTION Study of Vimseltinib in TGCT underscores their unwavering commitment to advancing the field of oncology and improving the lives of those affected by this challenging disease.
70. VirtualHealth
Category: Software and Data
VirtualHealth is at the forefront of transforming healthcare through innovative technology. With a focus on innovation and a value-based care approach, VirtualHealth is dedicated to empowering healthcare organizations to deliver to members optimized care experiences that address whole-person health and well-being. HELIOS® by VirtualHealth is an advanced solution for care management, utilization management, care coordination, disease management, and population health management. It enables government health plans, commercial payers, health systems, and specialty providers to streamline the administration of value-based care management and focus on providing better care and improving health outcomes and patient and employee satisfaction. Across the nation, some of the largest and most innovative healthcare organizations rely on HELIOS for care management, case management, disease management, and utilization management. Recent milestones include the launch of HELIOShub, the groundbreaking FHIR® Integration Platform as a Service (FiPaaS), expanding the HELIOS product family to include HELIOS, HELIOSum, HELIOSvisit, HELIOStext, and HELIOSgo, new partnerships with Edifecs and Itiliti Health, as well as participation in Amazon Web Services (AWS) Health Equity Program, all showcasing VirtualHealth's unwavering commitment to advancing healthcare.
71. Denali Therapeutics
Category: Biotech
Denali Therapeutics, based in South San Francisco, California, is dedicated to combating neurodegenerative diseases by surmounting scientific and clinical barriers. Their mission centers on delivering effective medicines to patients and their families, reshaping neurological healthcare. Denali's scientific strategy relies on three core principles: evaluating genetic targets, innovative brain delivery, and strategic biomarker usage for development.
With about 400 employees, Denali fosters a work environment driven by scientific rigor, impact-driven objectives, supportiveness, and collaboration. Recent developments include Denali's unveiling of key 2023 milestones, promising breakthroughs in neurodegeneration and lysosomal storage disease therapeutics. Additionally, their collaboration with Biogen to develop and commercialize the Antibody Transport Vehicle Program targeting Amyloid Beta underscores their unwavering commitment to advancing neurological healthcare.
72. Molli Surgical
Category: Medical Devices
MOLLI Surgical started with one patient’s voice — a patient who asked if there was a way to make her breast cancer journey better. Her voice led to the creation of MOLLI Surgical’s flagship wire and radiation-free technology, MOLLI® and its successor, MOLLI 2®. MOLLI Surgical’s precision system is intended to replace outdated procedures to mark lesions for surgical removal with greater precision, efficiency, and cost-effectiveness. MOLLI Surgical’s innovations ensure that surgeons and radiologists have the best possible tools in their hands to support a better patient experience.
MOLLI® has been recognized by TIME as one of 2022’s “Best Inventions” in the Medical Care category and named to Fast Company’s list of the “Next Big Things in Tech,” recognizing technology breakthroughs across industries that promise to transform the future. MOLLI Surgical is proud to build the advanced solutions that patients and physicians prefer.
73. Cambrian Bio
Category: Biotech
Cambrian Bio, headquartered in New York, is a pioneering clinical-stage drug development company dedicated to creating medicines that have the potential to treat and prevent some of today’s most debilitating diseases. Cambrian advances multiple scientific breakthroughs, each targeting a mechanistic driver of aging, through its pipeline companies led by its R&D team in collaboration with dedicated experts. This model enables Cambrian to efficiently develop a wide range of new drugs and form partnerships across the healthcare and research ecosystem.
Since its establishment in 2019, Cambrian secured $160 million in funding, advancing from seed to Series C, and expanded its portfolio to encompass more than ten preclinical and clinical stage companies across the US, UK, and EMEA regions, including a publicly traded affiliate. Moreover, it has achieved significant progress in moving several programs towards their milestones in under two years.
74. Eikon Therapeutics
Category: Biotech
Eikon Therapeutics, based in Hayward, CA, is a biopharmaceutical company at the forefront of scientific innovation. Founded by Nobel Prize laureates in 2014, the company utilizes technology at the intersection of biology, engineering, and chemistry to transform the treatment of life-threatening diseases. Eikon's discovery platform relies on cutting-edge microscopes that enable real-time, molecular-resolution tracking of protein movements within living cells. This technology directly measures the impact of chemical compounds on protein behavior in live cells, identifying elusive compound-protein interactions.
The company’s focus on visualizing disease-related protein mechanisms and using high-content datasets empowers data-driven hypotheses for the discovery of life-saving therapies. Furthermore, Eikon Therapeutics’s recent acquisition of global rights to clinical-stage assets and the announcement of an emerging drug development pipeline highlight their commitment to advancing healthcare globally.
75. Spartan Medical
Category: Medical Device
Spartan Medical is a leading provider of innovative medical technologies and solutions for healthcare providers, government agencies, schools, hospitals, and ambulatory surgery centers (ASCs). Located near Washington, D.C., the veteran-owned company has been recognized as a “top priority vendor” for the Veterans Health Administration - America's largest integrated health care system - and it has been awarded more than 700 federal government contracts.
Spartan Medical leads the charge for the mass adoption of single-use, sterile, pre-packaged instruments, which reduce infection risks, improve OR efficiency, reduce costs, increase profitability and improve patient outcomes. The initiative has positioned Spartan Medical as a major player in the ASC sector and among field-based military centers that need durable, surgery-ready instruments.
In 2022, Spartan Medical launched two technology solutions to help address the mental health crises plaguing college campuses and veteran communities. In addition, Spartan Medical joined forces with a food-as-medicine logistics platform to provide the Veteran HealthPak™, a comprehensive solution to address the clinical needs of the 13.8 million veterans who have one or more chronic health conditions. Spartan Medical’s vast network and experience have made it an industry leader for any organization seeking to buy or sell innovative medical technologies and solutions.
76. Eleanor Health
Category: Consumer HealthTech
Eleanor Health, headquartered in Waltham, Massachusetts, is a leading provider of mental health and substance use treatment, operating 32 clinics across seven states. Their mission is clear: to assist individuals struggling with mental health or addiction in living fulfilling lives. Eleanor Health takes a unique approach by treating addiction as a chronic illness.
Their evidence-based model encompasses medication, therapy, counseling, and connecting patients to essential resources, all delivered with utmost respect and compassion. What sets Eleanor Health apart is their commitment to transforming addiction treatment through value-based care. They meet patients where they are, whether through clinics, community settings, or innovative technology and field-based teams.
77. Establishment Labs
Category: Medical Devices
Establishment Labs Holdings Inc., based in Coyol, Alajuela, is a global medical technology company at the forefront of enhancing women's health through science and technology. With roughly 700 employees, the company specializes in Femtech solutions for breast health, aesthetics, and reconstruction. Since 2010, Establishment Labs has supplied over three million Motiva® devices to plastic and reconstructive surgeons across 85 countries, establishing a new benchmark for safety and patient satisfaction. Their Motiva Flora® tissue expander, the world's sole regulatory-approved expander with an integrated MRI conditional port using radio-frequency technology, has significantly improved breast reconstruction outcomes after cancer.
The company's latest breakthrough, Mia Femtech™, offers a minimally invasive solution for achieving breast harmony. These innovations are backed by a portfolio of over 200 patent applications and supported by more than 50 scientific studies. Establishment Labs operates two cutting-edge facilities in Costa Rica, adhering to ISO13485:2016 and FDA 21 CFR 820 standards under the MDSAP program. They are also launching Mia Femtech in Japan, solidifying their commitment to advancing women's health globally and revolutionizing breast aesthetics.
78. F2G
Category: Biotech
F2G, a clinical-stage biopharmaceutical firm headquartered in the UK with US and Austrian subsidiaries, is at the forefront of developing novel therapies to combat life-threatening invasive fungal infections. Their groundbreaking achievement is the creation of a new class of antifungal agents, the orotomides. These orotomides, unlike current antifungal agents, have a distinct mode of action, specifically targeting fungal dihydroorotate dehydrogenase (DHODH), a pivotal enzyme in fungal pyrimidine biosynthesis.
Olorofim, the lead candidate in this class, exhibits fungicidal activity against a wide range of mold infections, including rare and resistant strains that challenge existing therapies. In a strategic move, F2G partnered with Shionogi Co., Ltd. in 2022 to jointly develop and commercialize Olorofim in Europe and Asia. Recently, the FDA issued a Complete Response Letter for Olorofim's New Drug Application, prompting F2G to plan resubmission with additional data and analyses.
79. Freeline
Category: Biotech
Freeline is a biotechnology company headquartered in the UK with operations in the United States. The company focuses on developing gene therapies for chronic diseases. Freeline employs its proprietary AAV vector and capsid, known as AAVS3, along with novel promoters and transgenes, to deliver therapeutic genes into human liver cells. This approach enables the expression of missing or dysfunctional proteins in a patient's bloodstream.
Currently, Freeline is advancing FLT201, a gene therapy candidate, in a Phase 1/2 clinical trial for Gaucher disease type 1. Freeline also conducts research programs, including one for GBA1-linked Parkinson's disease, utilizing the same transgene as FLT201. With its innovative technology and a pipeline of potential therapies, the company strives to improve the lives of patients worldwide.
80. iECURE
Category: Biotech
iECURE is a gene editing company headquartered in Philadelphia, PA, focused on developing therapies utilizing mutation-agnostic in vivo gene insertion, or knock-in editing, for treating liver disorders with unmet medical needs. Their approach aims to replace dysfunctional genes with healthy copies, ensuring sustained gene expression and potentially curative outcomes, regardless of the genetic mutation. The company is led by an experienced management team with a track record in executing global orphan drug and gene therapy clinical trials, and bringing products to market.
iECURE collaborates with the University of Pennsylvania’s Gene Therapy Program (GTP) to enhance their pipeline of potential product candidates. The European Commission granted orphan designation to their lead product candidate, GTP-506, for treating Ornithine Transcarbamylase (OTC) deficiency. In 2022, the company secured $65 million in funding to advance their in vivo gene editing programs, particularly targeting rare pediatric liver diseases. iECURE's innovative vision and strategic alliances offer renewed hope to patients with liver disorders.
81. American Health Technology Group
Category: Software and Data
American Health Technology Group (AHTG) is a distinguished leader in providing best-in-class software solutions specifically designed for the healthcare staffing industry. With a laserfocus on this specialized sector, AHTG has become synonymous with innovation, reliability, and excellence.
AHTG’s mission statement is “to connect and empower healthcare organizations and clinicians through innovative workforce solutions”. AHTG understands the intricacies and demands of the healthcare industry, and how to empower healthcare organizations with tools that enhance efficiency, streamline operations, and elevate staffing management.
82. Immunocore
Category: Biotech
Immunocore is an industry standout in researching and developing biological therapies connected to the body’s T cell receptors. The immense practical applications of Immunocore’s research lie in oncology, and its program pipeline has turned out numerous advances in treatment over the last decade. With major industry partners including GlaxoSmithKline, AstraZeneca, and the Gates Foundation, the company is positioned to redefine how the world treats patients with cancer and infectious diseases.
Headquartered in Oxfordshire, England with offices in Pennsylvania and Maryland, Immunocore traces its history to its founding in 2008 as a spinoff of MediGene, and previously to T cell receptor technology developed by Dr. Bent Jakobsen at Oxford University in 1999. Although all of the company’s developments hold great potential for saving and improving human life at a tremendous scale, the initial testing of a new protocol for treating HIV has shown great promise, and that as well as other successes have spiked its stock to a new high.
83. InSightec
Category: Medical Devices
Insightec, a global healthcare company headquartered in Haifa, Israel, and Miami, with additional offices in München, Dallas, Shanghai, and Tokyo, is reshaping patient care with acoustic energy technology. With a workforce of over 400 professionals, Insightec leads the charge in medical innovation. At its core is the Exablate Neuro platform, which employs MRI-guided sound waves to treat medication-resistant Essential Tremor and Parkinson's Disease safely. Insightec collaborates with prestigious academic and medical institutions to explore future applications in neuroscience.
Recently, Insightec achieved CE Mark Approval and FDA Approval to expand its treatment options for Essential Tremor patients by addressing the second side, broadening its impact globally and in the United States. In 2022, Insightec secured a significant financing round of up to $200 million, affirming its position as a frontrunner in medical technology. This investment ensures their ongoing contributions to advancing patient care.
84. Karuna Therapeutics
Category: Biotech
Karuna is a clinical-stage biopharmaceutical company with a singular focus: creating and delivering transformative medicines for individuals living with psychiatric and neurological conditions. The company's team possesses a unique depth of expertise in neuroscience, encompassing research, development, and the commercialization of central nervous system (CNS) agents. What sets Karuna apart is their extensive clinical experience, which includes direct interaction with patients and caregivers. This hands-on involvement has reinforced their belief in the demand for innovative treatments that can assist individuals in navigating the complexities of these conditions.
Drawing upon their comprehensive knowledge of neuroscience, Karuna is actively exploring new avenues to develop medications that have the potential to make a profound impact on people's lives. The team's shared passion drives them toward a collective goal larger than themselves, motivating them to study and deliver medicines that promise substantial improvements for those affected by schizophrenia, dementia-related psychosis, and other psychiatric and neurological conditions. Karuna's vision is to lead the way in pioneering medicines that offer hope and meaningful relief to those facing these challenges.
85. eVideon
Category: Software and Data
eVideon is the leader in hospital smart room technology and digital workflow solutions. The company’s Vibe Health smart room platform automates clinical workflow, enhances communication, and transforms the care environment. Using its interactive TV, digital whiteboard, digital door sign, bedside tablet, and video visit solutions, eVideon delivers a personalized experience to patients and families, while easing the burden on care teams.
Notably, the company’s platform integrates with the hospital's Electronic Medical Record (EMR) and other installed systems to ensure accurate, real-time information is accessible to all throughout the care journey. Using automation, Vibe Health relieves nurses of non-clinical responsibilities and enables the care team to spend more time at the bedside. eVideon is reimagining the human experience in healthcare by delivering the digital patient room of the future today.
86. MeiraGTx
Category: Biotech
MeiraGTx is a clinical-stage gene therapy company known for its integrated approach. With six ongoing clinical programs and a portfolio of preclinical and research initiatives, the company is a leader in gene therapy innovation. MeiraGTx specializes in viral vector design, optimization, and gene therapy manufacturing. It has a gene regulation platform allowing precise control of gene expression via oral small molecules with a dynamic range exceeding 5000-fold. Led by an experienced management team, MeiraGTx focuses on addressing unmet medical needs in three key areas: inherited retinal diseases, neurodegenerative disorders, and severe xerostomia.
Initially concentrating on ocular, central nervous system, and salivary gland conditions, MeiraGTx plans to broaden its therapeutic scope to address a wide spectrum of severe diseases. With headquarters in both London and the USA, MeiraGTx recently achieved a significant milestone as its wholly-owned gene therapy manufacturing facility in Shannon, Ireland, received Commercial MIA Authorization for QC Testing, underscoring its commitment to advancing therapies.
87. NantHealth
Category: Software & Data
NantHealth is a leading healthcare technology company specializing in integrated healthcare delivery networks. Their cutting-edge technology solutions drive efficiency, personalized treatment, and collaboration within healthcare, bridging precision medicine and value-based care. They are widely recognized by providers and payers for their advanced software and devices. As a member of the NantWorks ecosystem, NantHealth offers enterprise solutions to transform complex data into actionable insights, serving various industries like healthcare, life sciences, logistics, and telecommunications. Their expertise lies in streamlining data movement, interpretation, and visualization while ensuring security and scalability.
NantHealth's product portfolio includes real-time coverage decision support platforms for payer-provider collaboration and comprehensive data solutions for multi-data analysis, reporting, and professional services. With offices in El Segundo, California, Boston, Massachusetts, Philadelphia, Pennsylvania, and Belfast, Northern Ireland, they have a global reach. Recent achievements include NantHealth's HITRUST Risk-based, 2-year Certification for Eviti Connect, demonstrating their commitment to privacy and security. They've also secured $22.5 million in new financing from Highbridge and Nant Capital, solidifying their position as a forward-thinking industry leader.
88. Bastion Health
Category: Software and Data
Bastion Health, founded by Reza Amin and headquartered in Farmington, CT, stands as a pioneering force in men's healthcare. This innovative company has introduced the world to the concept of a comprehensive digital men's health clinic with a specific focus on reproductive and prostate health. Bastion Health's mission is to destigmatize and facilitate open conversations about men's health. They empower individuals to proactively manage their well-being, all from the comfort of their own homes. This is made possible through their groundbreaking AI-powered app, offering seamless access to urologists and men's health specialists.
Bastion Health’s app provides swift and hassle-free consultations, diagnostic testing, in-depth assessments, and tailored clinical treatment plans. Furthermore, the company supplies a wealth of on-demand educational content, ensuring that individuals are well-informed about their health and treatment options. In essence, Bastion Health redefines men's healthcare by merging convenience, accessibility, and expert medical guidance. It exemplifies a new era where men can take charge of their health with ease, making proactive healthcare a reality for everyone.
89. Neuro42
Category: Medical Devices
Founded in 2020 by a team of serial entrepreneurs, neuro42 is a cutting-edge medtech company dedicated to advancing the field of neuroscience through its innovative solutions. Headquartered in San Francisco, California, the company specializes in the development and commercialization of a portable MRI, robotic, and AI platform tailored for point-of-care imaging and interventions guided by live imaging. Notably, neuro42 boasts a substantial intellectual property portfolio, with over 40 patents, and has cultivated partnerships with esteemed institutions such as Harvard Medical School, the University of California, Berkeley, Massachusetts General Hospital, and John Hopkins, among others.
With relentless commitment to innovation, creative problem-solving, and to improving healthcare, neuro42 successfully developed the portable MRI system. The product suite integrates a range of patented technologies, facilitating efficient diagnosis and precision treatment of neurological conditions. The platform is designed to elevate both the patient and physician experience by requiring minimal set up and blending seamlessly into the procedural workflow, advancing neuroscience and improving healthcare outcomes.
90. PROCEPT BioRobotics
Category: Medical Devices
PROCEPT BioRobotics, headquartered in Redwood Shores, CA, is a leading surgical robotics company with approximately 400 employees. Their mission revolves around transforming urology patient care. They specialize in developing, manufacturing, and marketing the AquaBeam® Robotic System, an advanced surgical robotics platform designed for minimally invasive urologic procedures, initially focusing on treating benign prostatic hyperplasia (BPH), a condition affecting 40 million men in the United States. Their proprietary AquaBeam system provides Aquablation therapy, integrating real-time imaging, personalized treatment planning, automated robotics, and heat-free waterjet ablation for precise and rapid removal of prostate tissue.
PROCEPT BioRobotics has amassed substantial clinical evidence, supported by nine clinical studies and 150+ peer-reviewed publications, demonstrating the clinical advantages of Aquablation therapy. Notably, the company recently received a U.S. FDA Investigational Device Exemption for exploring Aquablation Therapy for Prostate Cancer. They've also announced the commencement of commercial Aquablation Therapy procedures in Japan and secured United Healthcare coverage for this groundbreaking treatment, marking their commitment to enhancing urological patient care worldwide.
91. Vizzia Technologies
Category: Software & Data
Vizzia Technologies is a leading software and managed service provider of real-time location systems (RTLS) for healthcare organizations, to include several of the largest hospitals and health systems in America.
Its award-winning InVIEW℠ software platform provides real-time, actionable data and process visibility, empowering hospitals to enhance efficiencies and patient care. With extensive experience serving leading health systems, and industry recognition as a top healthcare technology company, Vizzia produces meaningful results for its hospital customers - lowering costs, increasing productivity and improving care.
Vizzia received the Frost & Sullivan 2023 RTLS Company of the Year Award in recognition of its best practices in innovation, performance and unmatched customer care.
92. Ro
Category: Consumer HealthTech
A leader in the development and advancement of at-home, direct-to-patient healthcare solutions, New York telehealth company Ro has long been dedicated to breaking down barriers between people and providers. Ro features a vertically integrated platform that empowers individuals to follow a complete path to total health, from diagnosis to treatment, all while avoiding the expensive and difficult ins and outs of dealing with health insurance. The company has facilitated over eight million telehealth visits, helping individuals living in underserved areas get treatment in mental health, sexual health, and general health issues.
From the moment of its founding under the name Roman in 2017, Ro has raised several brisk rounds of investor funding that have allowed it to grow its product line rapidly and build a dedicated customer base. Though it got its start as a discreet, simple method of treating ED, Ro built itself into a provider of whole health solutions, garnering praise for its offerings in smoking cessation, women’s health, and most recently, at-home COVID testing.
93. SI-BONE
Category: Biotech
SI-BONE, headquartered in Santa Clara, California, is a global leader in surgical technology for sacropelvic musculoskeletal disorders. Clinical studies have revealed that 15% to 30% of chronic lower back pain originates from the sacroiliac (SI) joint. In 2009, SI-BONE introduced the groundbreaking iFuse Implant System®, a minimally invasive surgical solution for SI joint fusion and dysfunction treatment. Thousands of surgeons worldwide have used iFuse to treat tens of thousands of patients effectively.
Furthermore, SI-BONE has expanded its iFuse Technology® platform to include iFuse-3D™ and iFuse-TORQ®, gaining regulatory clearance for applications in pelvic trauma and adult spinal deformity. Recent achievements include a remarkable 45% sales growth in Q1 and the compatibility announcement of the iFuse Bedrock Granite® Implant System with select Medtronic CD Horizon® Solera® 5.5/6.0 System Rods. These successes underscore SI-BONE's leadership in the field, demonstrating their commitment to revolutionizing musculoskeletal care.
94. SiBionics
Category: Medical Devices
Shenzhen SiBionics Co. Ltd., a venture-backed MedTech startup, specializes in developing and commercializing advanced active implantable medical devices and medical imaging artificial intelligence. The company has successfully incubated four key projects, including Retinal Prosthesis, Continuous Glucose Monitoring, AI Diabetic Retinopathy Screening, and Gastric Cancer Screening, with more innovations in the pipeline.
Notably, SiBionics recently unveiled the SIBIO KS1 CKM, a breakthrough product for Ketone Level Monitoring, marking a significant advancement in healthcare technology. In 2022, SiBionics secured a substantial $72 million in funding during a Series D round, underscoring its rapid growth and investor confidence in its ability to shape the future of healthcare through pioneering medical technologies.
95. Standard BioTools
Category: Biotech
Standard BioTools Inc., previously known as Fluidigm Corporation, operates with a focused mission: to accelerate breakthroughs in human health through innovative tools. Headquartered in South San Francisco, California, with approximately 500 employees, the company is a prominent player in biomedical research. Standard BioTools is known for its portfolio of next-generation technologies, empowering biomedical researchers to develop medicines more efficiently. Their proprietary mass cytometry and microfluidics technologies provide reliable insights into health and disease, translating scientific discoveries into improved patient outcomes.
Standard BioTools notably collaborates with a diverse range of clients, including academic institutions, government agencies, pharmaceutical companies, biotech firms, and research labs focused on various fields. With a global reach, the company addresses critical needs in translational and clinical research, particularly in oncology, immunology, and immunotherapy. In 2022, the company partnered with Visiopharm to develop image analysis solutions for Hyperion and Hyperion+ Imaging Systems, enhancing research capabilities. Additionally, Standard BioTools introduced the X9 Real-Time PCR System, a high-capacity genomics platform, further solidifying its leadership in the industry.
96. Supernus Pharmaceuticals
Category: Biotech
Supernus Pharmaceuticals is a pharmaceutical company specializing in central nervous system (CNS) disease treatments. With a history spanning 30 years, it evolved from a standalone developer to a subsidiary of Shire plc and later became Supernus Pharmaceuticals Inc. The company maintains a strong focus on CNS diseases, driving advancements in healthcare to benefit patients worldwide. It markets products in the U.S. through its dedicated sales force and seeks global collaborations for product licensing.
Supernus Pharmaceuticals offers treatments such as Qelbree® for ADHD in children, Trokendi XR® for migraine prophylaxis and epilepsy, Oxtellar XR® for epilepsy, Apokyn® for advanced Parkinson’s disease, Myobloc® for cervical dystonia and chronic sialorrhea in adults, and Xadago® as an adjunctive therapy for Parkinson's disease patients. Additionally, the company is actively developing SPN-812 for adult ADHD, an apomorphine infusion pump for Parkinson’s disease, SPN-820 (NV-5138) for treatment-resistant depression, and SPN-817 for epilepsy.
97. Synthego
Category: Software & Data
Synthego, headquartered in Menlo Park, California, is a genome engineering company focused on advancing life science research and development for better human health. They achieve this through the integration of machine learning, automation, and gene editing technologies to create scalable scientific platforms. At Synthego, their platform technologies, which encompass proprietary hardware, software, bioinformatics, chemistries, and molecular biology, are engineered to support various research areas, including basic research, target validation, and clinical trials. Their impact is substantial, with their technologies cited in numerous peer-reviewed publications and adopted by both commercial and academic researchers, as well as therapeutic drug developers.
Synthego plays a pivotal role in enabling genome editing at an unprecedented scale, setting the stage for the future of medicine. In recent news, Synthego has expanded its partnership with bit.bio to develop safer and more efficient genetic engineering platforms for human cell therapies. They've also formed an alliance with ATCC to advance gene editing in mammalian and mouse cell lines. Furthermore, the company has opened a state-of-the-art GMP Guide RNA Manufacturing Facility to support the production of CRISPR-based genomic medicines.
98. Trinity Biotech
Category: Biotech
Trinity Biotech specializes in the development, manufacture, and marketing of diagnostic test kits. Their success is based on achieving excellence in all they do. The test kits they manufacture are used in the clinical laboratory and point-of-care segments of the diagnostic market to detect infectious diseases, sexually transmitted diseases, autoimmune disorders, hemoglobin disorders, and in the detection, monitoring, and control of diabetes. They are also a significant provider of raw materials to the life sciences industry.
Quoted on the NASDAQ exchange, and with facilities spanning Europe and America, their products are sold in more than 110 countries. They reach customers worldwide through their sales force and a network of international distributors and strategic partners. Recently, Trinity Biotech announced it has received 510(k) clearance from the U.S. FDA for the Premier Resolution System. They also announced the closing of a $30 million sale of their Life Sciences Supply Business to Biosynth.
99. Ultima Genomics
Category: Biotech
Ultima Genomics, headquartered in Newark, CA, is a company with a clear mission: to revolutionize genomics by scaling up genomic information. Their focus is on driving advancements in biology and human health through cost-effective sequencing technology. In a world on the verge of a biological revolution, Ultima Genomics aims to provide the abundant genomic data needed to understand the complexities of biology. Ultima Genomics has developed an innovative sequencing architecture that lowers sequencing costs significantly, removing the traditional trade-offs scientists and clinicians face when using genomic data.
With a workforce of 300 employees, Ultima Genomics has recently partnered with Genome Insight, Integrated DNA Technologies, New England Biolabs, and 10x Genomics to expand the applications of their sequencing platforms. These collaborations will bring affordable whole genome sequencing to cancer patients and seamlessly integrate cutting-edge single-cell applications. Ultima Genomics is leading the charge in reshaping the genomics landscape, making genomic information more accessible and impactful than ever before.
100. Vapotherm
Category: Medical Devices
Vapotherm, Inc., headquartered in Exeter, New Hampshire, is a leader in the development and manufacturing of advanced respiratory technology. With over 4.0 million patients benefiting from their innovative high velocity therapy® systems, the company has become a pivotal player in the healthcare industry. Trading on the NYSE under the ticker symbol "VAPO," Vapotherm continues to expand its horizons. Recent developments include a successful $23 million private placement.
Notably, Vapotherm, Inc. stands as the pioneering inventor of the high flow nasal cannula and its advanced iteration, Vapotherm high velocity therapy. The Precision Flow® system, a testament to their commitment to innovation, offers clinicians a reliable tool suitable for diverse patient populations. This technology is particularly vital in emergency departments (ED) and intensive care units (ICU), providing oxygenation and mask-free respiratory support with the added comfort of heated humidified high flow. With a dedicated team of over 300 employees, the company remains steadfast in its mission to improve the lives of patients with chronic or acute breathing disorders through comfortable, non-invasive respiratory solutions.
