Toxic Waste Dump: Research Team Finds Readthrough Key to Brain Clearance

Washington University School of Medicine researchers have uncovered an entirely new druggable pathway with the potential for revolutionary treatment and/or prevention of Alzheimer’s dementia. Using mice as test subjects, the researchers devised a means of increasing systemic clearance of waste products via exploitation of readthrough, a genetic quirk wherein the brain protein aquaporin 4 is synthesized with a seemingly superfluous...